β-Amyloid protein (Aβ) is formed by the precursor β-Amyloid Precursor Protein (β-APP, APP) through the action of enzymes. It is commonly found in the human brain, heart, kidneys and other organs. However, when APP is hydrolyzed to form β-Amyloid and abnormally accumulates in cell tissues, it becomes toxic to cells and causes cell pathology and death. Aβ1-40 is a β-Amyloid protein composed of 40 amino acids. It forms plaques or fiber tangles in diseased or aged brain tissue. The most famous of these is Alzheimer's disease (AD). Other neurodegenerative diseases are also related to the accumulation and toxicity of β-Amyloid protein.

This product uses the immunomagnetic reduction assay to quantitatively detect the concentration of Aβ1-42 in human plasma, or the ratio of its concentration and the concentration measured by the "Magqu" β-Amyloid 1-42 (Aβ1-42) IMR reagent (Aβ1-42/Aβ1-40) as the detection value. It needs to be combined with clinical data and other test results as a reference to assist in the diagnosis of Alzheimer's disease.

Just can be used as one of the reference materials for clinical diagnosis of Alzheimer's disease, and the results of this test cannot be used as the only basis for diagnostic confirmation, currently.